abstract：Background:Several studies have investigated hypopharyngeal cancer (HC) risk in combination with xenobiotic metabolism-related genetic polymorphisms and the burden of alcohol consumption and smoking in European countries but not in East Asian countries. Patients and Methods:This hospital-based case-control study invol...

journal_title：Journal of cancer research and therapeutics

authors： Yamashita Y,Ikegami T,Suzuki M,Hirakawa H,Maeda H,Yamada S,Deng Z,Kondo S,Kinjyo H,Kiyuna A,Agena S,Uehara T,Ganaha A

更新日期：2019-07-01 00:00:00

abstract：Background and Objectives:Quid-chewing habit is a common and old tradition in India. It causes various potentially malignant disorders. Therefore, a study was undertaken to analyze the association of various quid-chewing habit patterns and different oromucosal lesions. Materials and Methods:A cross-sectional study was...

journal_title：Journal of cancer research and therapeutics

authors： Avinash Tejasvi ML,Anulekha CK,Afroze MM,Shenai KP,Chatra L,Bhayya H

更新日期：2019-07-01 00:00:00

abstract：Background:The aim of this study is to determine the prognostic factors which affect both disease-free survival (DFS) and overall survival (OS) in thyroid papillary carcinoma with clinical lateral lymph node metastasis. Methods:One hundred and three papillary thyroid carcinomas diagnosed in adult patients received the...

journal_title：Journal of cancer research and therapeutics

authors： Yuksel UM,Turanli S,Acar Y,Berberoglu U

更新日期：2019-07-01 00:00:00

abstract：:A solitary fibrous tumor is a rare spindle cell neoplasm originating from the mesenchyme. This type of tumor of the orbit is very uncommon and can be misdiagnosed as a hemangiopericytoma, fibrous histiocytoma, meningioma, or neurofibroma. We report an orbital solitary fibrous tumor in an 18-year-old male, with slow-gr...

journal_title：Journal of cancer research and therapeutics

authors： Sayit AT,Elmali M,Gul A,Sullu Y

更新日期：2019-07-01 00:00:00

abstract：Aim of Study:Metabolic syndrome (MetS) is an abnormality that increases the risk of cardiovascular disease and diabetes. In the recent years, studies showed that MetS is associated with increased risk of incidence, aggressiveness, and mortality of prostate cancer (PCa). We examined the influence of MetS at final pathol...

journal_title：Journal of cancer research and therapeutics

authors： Caliskan S,Kaba S,Özsoy E,Keleş MO,Koca O,Akyüz M,Karaman MI

更新日期：2019-03-01 00:00:00

abstract：Objective:Undesired neutron contamination imposed to patients during treatment is among the main factors increasing the risk of secondary cancer in radiotherapy. This additional undesirable dose is due to neutron contamination production in high-energy accelerators. In this study, neutron contamination is investigated ...

journal_title：Journal of cancer research and therapeutics

authors： Khajetash B,Bahreyni Toossi MT,Ghorbani M,Jahangiri M,Akbari F

更新日期：2019-03-01 00:00:00

abstract：:A 29-year-old hypertensive male with von Hippel-Lindau (VHL) syndrome came to the Endocrinology department for evaluation. Contrast-enhanced computed tomography of the abdomen revealed an adrenal mass, bilateral renal cell carcinoma, and multiple pancreatic cysts. The hormonal investigations for adrenal mass were norm...

journal_title：Journal of cancer research and therapeutics

authors： Palui R,Kamalanathan S,Sahoo J,Dorairajan LN,Badhe B,Gochhait D

更新日期：2019-03-01 00:00:00

abstract：Purpose:The aim of the study is to study the feasibility of gamma-ray-detection-based precision dose measurement of 125I seed brachytherapy in solid water. Materials and Methods:Seven group 125I seeds with different activities were put into a hole in the center of solid water individually. Each group had ten seeds, an...

journal_title：Journal of cancer research and therapeutics

authors： Zhang H,Liang Y,Qiu G,Wang Z,Dev D,Liu Z,Li H,Yu H,Chen J,Sui A,Wang J,Shi G

更新日期：2019-01-01 00:00:00

abstract：Background:We assessed the frequency of epigenetic lesions, including lymphoid-specific helicase (LSH), 5-hydroxymethylcytosine (5-hmC) and E2F1, and the possible correlations among molecular findings, phenotype, clinical features, and outcome. Methods:We investigated 181 paraffin-embedded B-cell lymphoma samples usin...

journal_title：Journal of cancer research and therapeutics

authors： Ouyang C,Deng Z,Zhou J,Fu C,Liu S,Tao Y,Xiao D

更新日期：2019-01-01 00:00:00

abstract：Background:Natural orifice transluminal endoscopic surgery (NOTES) is a minimal invasive treatment. However, tissue dissection under endoscopy is still challenging due to the flexibility of endoscopy body and there is still no effective method for establishing a tunnel towards the targeted area. We previously showed th...

journal_title：Journal of cancer research and therapeutics

authors： Sun X,Yu L,Zhu J,Zu S,Ding J,Liu Y

更新日期：2019-01-01 00:00:00

abstract：:Interstitial permanent radioactive seed implantation delivers a high local dose to tumors and sharply drops off at surrounding normal tissues. Radioactive seeds implanted via ultrasound or computed tomography (CT) guidance are minimally invasive and facilitate quick recovery. Transrectal ultrasound-guided 125I seed im...

journal_title：Journal of cancer research and therapeutics

authors： Wang J,Chai S,Wang R,Zheng G,Zhang K,Huo B,Huo X,Jiang Y,Ji Z,Jiang P,Peng R

更新日期：2019-01-01 00:00:00

abstract：Background:Conventional magnetic resonance imaging (MRI) does not accurately evaluate lymph node (LN) status, which is essential for the treatment and prognosis assessment in patients with rectal cancer. Objective:The aim of this study is to evaluate the diagnostic value of intravoxel incoherent motion (IVIM) MRI in d...

journal_title：Journal of cancer research and therapeutics

authors： Long L,Zhang H,He X,Zhou J,Guo D,Liu X

更新日期：2019-01-01 00:00:00

abstract：Background and Aim of Study:The role of E-cadherin (CDH1) gene-160 C>A (rs16260) promoter polymorphism in colorectal cancer (CRC) still remains inconclusive. The aim of this study is to investigate the associations between the CDH1-160 C>A polymorphism with the susceptibility and clinicopathological development of CRC ...

journal_title：Journal of cancer research and therapeutics

authors： Bahadir A,Eral G,Budak M,Shimamoto F,Korpinar MA,Erdamar S,Tuncel H

更新日期：2019-01-01 00:00:00

abstract：Context:Tyrosine kinase inhibitors (TKIs) targeting epidermal growth factor receptor (EGFR) play an indispensable role in the treatment of non-small cell lung cancer (NSCLC), leading to a survival major breakthrough, but there remains no uniform standard for predicting the efficacy of TKI therapy. Aims:We retrospectiv...

journal_title：Journal of cancer research and therapeutics

authors： Yu S,Wang X,Wang X,Wu X,Xu R,Wang X,Zhang X,Zhang C,Chen K,Cheng D,Wenfeng L

更新日期：2019-01-01 00:00:00

abstract：Context:Familial adenomatous polyposis (FAP) is an autosomal dominant disorder. Colorectal cancer (CRC) has been implicated as the most common cause of death in FAP patients, especially in those with coexisting CRC at initial diagnosis (FAP-CRC). Aim:We aimed to determine the survival rate of FAP-CRC and the factors a...

journal_title：Journal of cancer research and therapeutics

authors： Mirinezhad SK,Moaddab SY,Bonyadi MJ,Shirmohammadi M,Eftekharsadat AT,Somi MH

更新日期：2019-01-01 00:00:00

abstract：Objective:The aim of this study is to probe in the inhibitory effects of ginsenoside Rg3 on the expression of hypoxia-induced factor-1α (HIF-1α) and vascular endothelial growth factor (VEGF) in human gastric cancer cells. Materials and Methods:Human gastric cancer BGC823 cells were divided into the control group and e...

journal_title：Journal of cancer research and therapeutics

authors： Li B,Qu G

更新日期：2019-01-01 00:00:00

abstract：Background:To evaluate the usefulness of preoperative imaging with F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) for noninvasive risk assessment of gastrointestinal stromal tumor (GIST). Materials and Methods:A retrospective review including 32 patients with pathologically proven GIST. Preoperative FD...

journal_title：Journal of cancer research and therapeutics

authors： Kwon Y,Park E,Pahk K,Kim S,Kim MJ,Graf D,Park S

更新日期：2019-01-01 00:00:00

abstract：Aim:The aim of this study is to identify an ideal location of isocenter in intensity-modulated radiotherapy (IMRT) treatment plans. Materials and Methods:A total of 28 clinical target volumes and 4 English capital letters (C, L, T, and H) target volumes were considered in this study. Two IMRT treatment plans were gene...

journal_title：Journal of cancer research and therapeutics

authors： Mandal A,Asthana AK,Pradhan S,Shahi UP,Choudhary S

更新日期：2019-01-01 00:00:00

abstract：:Tailgut cysts (TGCs) are rare congenital lesions derived from the remnants of primitive hindgut and are usually lined by squamous, transitional, or glandular epithelium. Malignant transformation in TGC may occur which is still rarer. Most common malignancies that arise from these cysts are adenocarcinomas. Preoperativ...

journal_title：Journal of cancer research and therapeutics

authors： Valecha J,Ojha SS,Sharma A,Nilkanthe R

更新日期：2019-01-01 00:00:00

abstract：Background/Aim:Percutaneous thermal ablation combined with transarterial chemoembolization (TACE) becomes a treatment option for unresectable hepatocellular carcinoma (HCC). This study aims to investigate the safety and feasibility of percutaneous thermal ablation combined with simultaneous TACE for patients with HCC ≤...

journal_title：Journal of cancer research and therapeutics

authors： Wu M,Gao S,Song H,Zhang Z,Wang J,Liu R,Wang X,Cheng J,Luo J,Liu Q,Chen Y,Yan Z,Liu L

更新日期：2019-01-01 00:00:00

abstract：Background:Apatinib has been approved for the treatment of advanced gastric adenocarcinoma and gastric-esophageal junctional adenocarcinoma, but its efficacy is unknown for other advanced solid tumors. Aims and Objectives:We retrospectively reviewed the use of apatinib for multiple advanced-stage non-gastric cancers. ...

journal_title：Journal of cancer research and therapeutics

authors： Wu X,Wang H,Wu Y,Jin J,Zhan Y,Zhu G,Zhang F,Zhang C,Gan J,Li W

更新日期：2019-01-01 00:00:00

abstract：Objectives:Increasing evidence suggests that Wnt5a plays an important role in tumorigenesis. In particular, its expression is downregulated in hepatocellular carcinoma (HCC). The aim of this study was to explore the effect of Wnt5a overexpression on HCC cells. Materials and Methods:We transfected the human HCC cell li...

journal_title：Journal of cancer research and therapeutics

authors： Wang T,Liu X,Wang J

更新日期：2019-01-01 00:00:00

abstract：Context:The metastasis of liver cancer is a major cause of clinical treatment failure, restrain, and control the cancer metastasis is the major strategy of the treatment and prevention of the disease. Special AT-rich sequence-binding protein 1 (SATB1) gene was overexpressed in many malignant tumors and considered as a ...

journal_title：Journal of cancer research and therapeutics

authors： Xu C,Guo H,Kong D,Pang D,Ding Y

更新日期：2018-12-01 00:00:00

abstract：Objective:The objective of this paper is to identify ego networks and pathways in rheumatoid arthritis (RA) based on EgoNet algorithm and pathway enrichment analysis. Materials and Methods:The ego networks were identified based on the EgoNet algorithm which was comprised four steps: inputting gene expression data and ...

journal_title：Journal of cancer research and therapeutics

authors： Zhou WZ,Miao LG,Yuan H

更新日期：2018-12-01 00:00:00

abstract：Aim of Study:The conclusions on the association between glutathione S-transferase P1 (GSTP1) gene polymorphism and lung cancer risk are still debated. This meta-analysis was performed to update the association between GSTP1 and the risk of lung cancer. Materials and Methods:The association investigations were identifi...

journal_title：Journal of cancer research and therapeutics

authors： Liu WZ,Sun Y,Feng X,Bi XH,Liu T,Zhou HF

更新日期：2018-12-01 00:00:00

abstract：Aim of Study:The roles of autophagy performed in chemotherapy-induced cell death or proliferation inhibition were still in debate. In this study, we aimed to disclose the function of autophagy in chemotherapy of HCT-116 colon cells. Materials and Methods:Pharmacological and genetic methods were applied to induce and i...

journal_title：Journal of cancer research and therapeutics

authors： Yang JW,Zhang QH,Liu T

更新日期：2018-12-01 00:00:00

abstract：Background:Nuclear factor kappa B (NFkB-light-chain-enhancer of activated B-cells) expression and its regulation is a key role in the development of number of malignancies, as NFkB mediates the balance between cell death and its survival. Therefore, NFkB regulation constitutes an attractive target to overcome the resis...

journal_title：Journal of cancer research and therapeutics

authors： Iqbal B,Ghildiyal A,Singh S,Siddiqui S,Kumari P,Arshad M,Mahdi AA

更新日期：2018-12-01 00:00:00

abstract：:Masseter hypertrophy is a characteristic condition resulting from an increase in the size of the muscle mass. At times, it produces significant facial asymmetry and is an important finding in the differential diagnosis of similar located entities. A proper diagnosis of this condition would avoid more aggressive and un...

journal_title：Journal of cancer research and therapeutics

authors： Naphade VV,Kedia SG,Patil P,Khare S

更新日期：2018-12-01 00:00:00

abstract：Purpose:Glioblastoma (GBM) is characterized by early relapse and mortality. Treatment resistance could be a characteristic exhibited by pro-genitor neoplastic cells that reside in the subventricular zone (SVZ). This retrospective study was conducted to assess the correlation of SVZ doses and survival in patients with G...

journal_title：Journal of cancer research and therapeutics

authors： Mathew BS,Kaliyath SB,Krishnan J,Bhasi S

更新日期：2018-10-01 00:00:00

abstract：Aim of Study:Prostate cancer (PCa) is one of the most common cancers among men and has become a significant health problem in developing and developed countries. Prostate-specific antigen (PSA) is a useful marker for screening and monitoring the patients. In this study, the author aimed to detect the prevalence of PCa ...

journal_title：Journal of cancer research and therapeutics

authors： Çalışkan S

更新日期：2018-10-01 00:00:00

abstract：Introduction:Cancer is one of the leading causes of mortality in the world and there are many types of cancer. The current treatments against cancer are surgery, chemotherapy, and radiation therapy, but these come with varied side effects as they harm noncancer cells too. Therefore, search for new treatments is one of ...

journal_title：Journal of cancer research and therapeutics

authors： Yadav A,Mendhulkar VD

更新日期：2018-10-01 00:00:00

abstract：Background:Colorectal cancer (CRC) is the second most diagnosed cancer often identified during the later stages of carcinogenesis. Orientin, a C-glycoside of luteolin, is well known for its versatile therapeutic action toward oxidative stress-induced cellular response may exert chemoprevention against CRC. Materials a...

journal_title：Journal of cancer research and therapeutics

authors： Thangaraj K,Natesan K,Settu K,Palani M,Govindarasu M,Subborayan V,Vaiyapuri M

更新日期：2018-10-01 00:00:00

abstract：:Plasma cell leukemia (PCL) is a rare and an aggressive form of plasma cell dyscrasias. We report a 67-year-old male with PCL which developed while on imatinib mesylate (IM) therapy 38 months after diagnosis of chronic myeloid leukemia (CML). The patient has been treated successfully with bortezomib, melphalan and pred...

journal_title：Journal of cancer research and therapeutics

authors： Maral S,Bakanay SM,Yikilmaz AS,Dilek I

更新日期：2018-10-01 00:00:00

abstract：Objective:The association between asthma and the risk of prostate cancer remains elusive. We aimed to evaluate the relationship between asthma and the onset of prostate cancer. Methods:We searched PubMed, Embase, and Cochrane databases for articles that assessed the association of asthma with the risk of prostate canc...

journal_title：Journal of cancer research and therapeutics

authors： Li W,Mao S,Tu M,Ge X,Li K,Xie F,Song Y,Miao Y

更新日期：2018-09-01 00:00:00

abstract：Aims:To explore the biological roles of alpha-fetoprotein (AFP), a tumor-associated antigen in human hepatocellular carcinoma (HCC). Materials and Methods:After knockdown of AFP in HepG2 cells by transfection of specific Stealth™ RNAi, the expression of AFP were detected by reverse transcription polymerase chain react...

journal_title：Journal of cancer research and therapeutics

authors： Yang X,Chen L,Liang Y,Si R,Jiang Z,Ma B,Gao P

更新日期：2018-09-01 00:00:00

abstract：Objective:Conflicting data have been reported regarding the association between perioperative blood transfusion (PBT) and clinical outcomes for prostate cancer patients. We conducted a systematic review and meta-analysis to evaluate the impact of PBT on cancer survival and recurrence for patients who underwent radical ...

journal_title：Journal of cancer research and therapeutics

authors： Pushan Z,Manbiao C,Sulai L,Jun L,Ruidong Z,Hanshen Y

更新日期：2018-09-01 00:00:00

abstract：Aim:This randomized phase III trial compared hepatic arterial infusion (HAI) chemotherapy with 5-fluorouracil (5-FU) followed by uracil/tegafur (UFT) and leucovorin (LV) versus UFT/LV alone for patients with curatively resected liver metastases from colorectal cancer (CRC). Methods:The study was designed to include 28...

journal_title：Journal of cancer research and therapeutics

authors： Kusano M,Aoyama T,Okabayashi K,Hirata K,Tsuji Y,Nakamori S,Asahara T,Ohashi Y,Yoshikawa T,Sakamoto J,Oba K,Saji S

更新日期：2018-09-01 00:00:00

abstract：:Ectopic extrarenal renin-producing tumor is a rare disease with approximately 30 case reports in English literature. We herein present the first case of renin-producing germ cell tumors in the pineal apparatus and mediastinum. A 26-year-old man who had undergone craniotomy for the treatment of pineal tumor was found t...

journal_title：Journal of cancer research and therapeutics

authors： Uematsu M,Yokouchi H,Tanino Y,Munakata M

更新日期：2018-09-01 00:00:00

abstract：Background and Objectives:Human chorionic gonadotropin-β (hCGβ) is a hormone glycoprotein usually secreted by trophoblastic cells in early pregnancy and helps in growth and development of the embryo. While many trophoblastic and nontrophoblastic malignancies express elevated levels of hCGβ in serum, increased immunohis...

journal_title：Journal of cancer research and therapeutics

authors： Meda S,Reginald BA,Reddy BS

更新日期：2018-07-01 00:00:00

abstract：Introduction:Oxaliplatin-induced neurotoxicity is the single main dose-limiting factor in the treatment of colorectal cancer. The degree of neurotoxicity may be either acute and reversible or observed as cumulative and chronic peripheral nerve damage leading to peripheral neuropathy (PNP), walking difficulties, extremi...

journal_title：Journal of cancer research and therapeutics

authors： Banach M,Zygulska AL,Krzemieniecki K

更新日期：2018-07-01 00:00:00